Melanosome transfer, photoreception and toxicity assays in melanophores
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منابع مشابه
Rab32 Regulates Melanosome Transport in Xenopus Melanophores by Protein Kinase A Recruitment
Intracellular transport is essential for cytoplasm organization, but mechanisms regulating transport are mostly unknown. In Xenopus melanophores, melanosome transport is regulated by cAMP-dependent protein kinase A (PKA). Melanosome aggregation is triggered by melatonin, whereas dispersion is induced by melanocyte-stimulating hormone (MSH). The action of hormones is mediated by cAMP: High cAMP ...
متن کاملMelanophores: Smooth Muscle Cells in Disguise
Melanophores are specialized cells derived from the neural crest that contain membrane bound vesicles called melanosomes. Melanosomes are filled with melanin, a dark, nonfluorescent pigment that plays a principal role in physiological color adaptation of animals. Melanophores regulate melanosome trafficking on cytoskeletal filaments to generate a range of striking chromatic patterns. The mechan...
متن کاملEffects of somatolactin on melanosome aggregation in the melanophores of red drum (Sciaenops ocellatus) scales.
The effects of purified red drum somatolactin on pigment movement in red drum scales were studied in vitro and in vivo. The integument became pale within 2 min following an intramuscular injection of somatolactin (1 nmol/g body weight) in fish held in a black-background aquarium, and gradually regained its black coloration during the subsequent 30 min. No melanosome aggregation was observed in ...
متن کاملControl of melanosome movements in isolated skin melanophores of a catfish Clarias batrachus (Linn.).
Adrenergic and cholinergic receptors have been studied in isolated skin melanophores of a catfish Clarias batrachus. Catecholamines induced a strong aggregatory effect on the melanophores. Melanosome aggregation induced by adrenaline and noradrenaline was partially blocked by alpha adrenergic receptor blockers and a beta receptor blocker. Cholinomimetic drugs aroused a significant dispersion of...
متن کاملTransport Properties of Melanosomes along Microtubules Interpreted by a Tug-of-War Model with Loose Mechanical Coupling
In this work, we explored theoretically the transport of organelles driven along microtubules by molecular motors of opposed polarities using a stochastic model that considers a Langevin dynamics for the cargo, independent cargo-motor linkers and stepping motion for the motors. It has been recently proposed that the stiffness of the motor plays an important role when multiple motors collectivel...
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تاریخ انتشار 2009